Start with slightly moist skin, right after cleansing & toning. Apply tiny dots all over your face - a little is enough. With short, quick strokes, apply the serum with your fingertips. While your face is still wet with the serum, tap lightly with fingertips to allow the serum to sink in better. Wait 3 minutes or more for your skin to absorb the goodness. Always follow with a moisturizer. Can be used day & night. Vitamin E: This serum is a concentrated source of this ultimate antioxidant and hydrator for skin. Works synergistically even better with the other ingredients in this mix. Vitamin B3: Helps brighten up skin by improving protein synthesis, fighting pigmentation, reducing irritation and inflammation. Helps skin retain moisture (i.e., look fuller and healthier). White willow bark: It contains salicylic acid - a beta hydroxy acid (BHA) that helps clear pores and exfoliate dead cells off the skin. You can't have bright without clear - and that's where white willow bark comes in. Licorice: Glycosides, saponins & flavonoids. In English, and on your skin, that translates to a very soothing ingredient that's effective at attacking pigmentation, giving the skin an even tone.